Description

Corticorelin Ovine is a synthetic peptide analog of the hypothalamic hormone corticotropin-releasing hormone (CRH). This compound is a critical diagnostic agent used to assess the functional capacity of the pituitary gland. It is primarily utilized by pharmaceutical manufacturers and clinical research organizations specializing in endocrinology and diagnostic development. The product is supplied as a high-purity material suitable for advanced pharmaceutical applications.

Application

• Diagnostic Pharmaceutical Ingredient: Primary use as the active pharmaceutical ingredient (API) in diagnostic kits for assessing adrenal and pituitary function (e.g., corticorelin stimulation tests).
• Clinical Research: Used as a standard or challenge agent in clinical studies investigating the hypothalamic-pituitary-adrenal (HPA) axis, stress response, and related endocrine disorders.
• Reference Standard: Serves as a high-purity chemical reference standard for quality control and analytical method development in pharmaceutical laboratories.
• Biochemical Research: Employed in life science research to study CRH receptor binding, signal transduction pathways, and the physiological effects of CRH.
• Veterinary Diagnostics: Potential application in veterinary medicine for diagnostic testing in animal models or livestock.

Basic Information

Product Name	Corticorelin Ovine
CAS No.	121249-14-7
Molecular Formula	C206H342N60O63S
Molecular Weight	4669.3 g/mol
Synonyms	Corticorelin, Ovine; Ovine Corticotropin-Releasing Hormone; Ovine CRH; hCRH (1-41), Ovine; Acthrel (brand name); Corticotropin-Releasing Factor, Ovine; CRF, Ovine; Corticoliberin, Ovine
EINECS	Contact for details

Quality Control

Our Corticorelin Ovine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identity confirmation by mass spectrometry and HPLC, purity assessment, and determination of related substances. We provide full traceability and support regulatory submissions. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with stringent in-house specifications suitable for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Bacterial Endotoxins	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.