Description

Histidyl-Glutamyl-Alanyl-Prolyl-Isoleucine is a synthetic peptide sequence of significant interest in biochemical research and pharmaceutical development. This compound serves as a crucial building block for studying protein-protein interactions, enzyme specificity, and as a potential precursor for novel therapeutic agents. It is primarily utilized by research institutions, biotechnology firms, and pharmaceutical companies engaged in peptide synthesis, drug discovery, and advanced biomedical studies.

Application

• Pharmaceutical Research: As a key intermediate in the synthesis of longer, biologically active peptides and peptidomimetics for drug discovery programs.
• Biochemical Studies: For investigating enzyme kinetics, substrate specificity, and mechanisms of action in proteolytic pathways.
• Diagnostic Development: Potential use as a component in the development of immunoassays or as a standard in analytical methods.
• Cosmeceutical R&D: Exploration in the formulation of bioactive skincare products targeting specific cellular processes.
• Academic Research: A valuable tool for universities and research institutes studying peptide chemistry, structure-activity relationships (SAR), and molecular biology.

Basic Information

Item	Details
Product Name	Histidyl-Glutamyl-Alanyl-Prolyl-Isoleucine
CAS No.	121119-48-0
Molecular Formula	C29H45N9O9
Molecular Weight	663.73 g/mol
Synonyms	HEAPI; H-Glu-Ala-Pro-Ile-OH (common abbreviation); Histidine-Glutamate-Alanine-Proline-Isoleucine; L-Histidyl-L-glutamyl-L-alanyl-L-prolyl-L-isoleucine; Pentapeptide HEAPI; (S)-2-((S)-2-((S)-2-((S)-2-((S)-2-Amino-3-(1H-imidazol-4-yl)propanamido)-5-carbamoylpentanamido)propanamido)pyrrolidine-1-carboxamido)-3-methylpentanoic acid
EINECS	Contact for details

Quality Control

Our Histidyl-Glutamyl-Alanyl-Prolyl-Isoleucine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide Certificates of Analysis (COA) detailing all specifications to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content (AAA)	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.