Description

1,3-Dioxan-2-One,5-Methyl-4-(1-Methylethyl)-,(4R-Trans)-(9Ci) CAS NO 121103-88-6 is a high-purity, stereochemically defined cyclic carbonate derivative. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate, enabling the synthesis of complex molecules with precise stereochemical control. It is essential for research and development in the pharmaceutical, agrochemical, and fine chemical industries, where its unique structure facilitates the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anti-inflammatory, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the development of advanced, stereoselective pesticides and herbicides, where the specific (4R-Trans) configuration can influence biological activity.
• Fine Chemical Production: Employed as a specialized monomer or reagent in the synthesis of performance chemicals, liquid crystals, and advanced polymers.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in academic and industrial research focused on developing new catalytic methodologies.
• Polymer Chemistry: Can be utilized in the ring-opening polymerization (ROP) to create functional polycarbonates with tailored properties for biomedical or specialty material applications.

Basic Information

Product Name	1,3-Dioxan-2-One,5-Methyl-4-(1-Methylethyl)-,(4R-Trans)-(9Ci)
CAS No.	121103-88-6
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	(4R,5S)-5-Isopropyl-4-methyl-1,3-dioxan-2-one; (4R-trans)-5-Methyl-4-(1-methylethyl)-1,3-dioxan-2-one; 5-Isopropyl-4-methyl-1,3-dioxan-2-one (stereoisomer); trans-5-Isopropyl-4-methyl-1,3-dioxan-2-one; Chiral cyclic carbonate; 4R,5S-5-Isopropyl-4-methyl-2-oxo-1,3-dioxane; (4R,5S)-4-Methyl-5-(propan-2-yl)-1,3-dioxan-2-one
EINECS	Contact for details

Quality Control

Our 1,3-Dioxan-2-One,5-Methyl-4-(1-Methylethyl)-,(4R-Trans)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (4R,5S)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.