Description

Fmoc-Pro-Phe-Oh CAS NO 120943-07-9 is a protected dipeptide building block, specifically Fmoc-L-prolyl-L-phenylalanine, widely used in solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise stereochemistry. It is an essential raw material for pharmaceutical R&D, particularly in the development of therapeutic peptides, and is also utilized in biochemical research and the synthesis of peptide-based materials.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the sequential assembly of custom peptide chains.
• Pharmaceutical Research & Development: Used in the discovery and synthesis of novel therapeutic peptide candidates targeting various diseases.
• Bioconjugation and Probe Development: Serves as a building block for creating labeled peptides used in diagnostic assays and imaging studies.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening.
• Academic and Industrial Research: A fundamental reagent for studying peptide structure, function, and interactions in biochemistry and molecular biology labs.
• Synthesis of Peptide Fragments: Used for the custom production of specific peptide sequences required for biological testing or as standards.

Basic Information

Product Name	Fmoc-Pro-Phe-Oh
CAS No.	120943-07-9
Molecular Formula	C30H30N2O5
Molecular Weight	498.57 g/mol
Synonyms	Fmoc-L-Prolyl-L-phenylalanine; Fmoc-Pro-Phe-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-prolyl-L-phenylalanine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-((S)-pyrrolidine-2-carboxamido)-3-phenylpropan-1-one; Fmoc-Pro-Phe; FMOC-PRO-PHE; Fmoc-Pro-Phe-Oh CAS NO 120943-07-9; N-α-Fmoc-L-prolyl-L-phenylalanine
EINECS	Contact for details

Quality Control

Our Fmoc-Pro-Phe-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically meeting standards for peptide synthesis applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, and is supplied with a detailed Certificate of Analysis (COA). We support compliance with cGMP and other relevant quality frameworks for pharmaceutical ingredient sourcing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	-40° to -50° (c=1, DMF)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.