Description

2,2,6-Trifluoro-1,3-Benzodioxol-5-Amine is a specialized fluorinated aromatic amine building block featuring a benzodioxole core. This compound is valued for its unique molecular architecture, which combines fluorine atoms and an amine group on a fused heterocyclic system, making it a critical intermediate for advanced synthesis. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials due to its rigid, fluorinated structure.
• Chemical Biology Probes: Employed in the synthesis of fluorescent tags or molecular probes for studying biological systems.
• Cross-Coupling Reactions: The aromatic amine group makes it a suitable substrate for Buchwald-Hartwig amination and other palladium-catalyzed transformations.

Basic Information

Product Name	2,2,6-Trifluoro-1,3-Benzodioxol-5-Amine
CAS No.	120934-03-4
Molecular Formula	C7H4F3NO2
Molecular Weight	191.11 g/mol
Synonyms	5-Amino-2,2,6-trifluoro-1,3-benzodioxole; 2,2,6-Trifluorobenzodioxol-5-amine; 2,2,6-Trifluoro-1,3-benzodioxol-5-ylamine; 5-Amino-2,2,6-trifluorobenzo[d][1,3]dioxole; 120934-03-4; 5-Amino-2,2,6-trifluoro-benzo[1,3]dioxole
EINECS	Contact for details

Quality Control

Our 2,2,6-Trifluoro-1,3-Benzodioxol-5-Amine is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.