Description

2-Amino-5-Pyrimidinecarboxyaldehyde is a versatile pyrimidine derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex heterocyclic molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of nucleoside analogs, kinase inhibitors, and other bioactive molecules targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that require a functionalized pyrimidine core.
• Ligand Synthesis: Serves as a precursor for creating chelating ligands and metal-organic frameworks (MOFs) in material science and catalysis.
• Fluorescent Dye & Sensor Development: Utilized in the construction of heterocyclic fluorophores and molecular sensors due to its reactive aldehyde and amino groups.
• Peptide & Conjugate Chemistry: The aldehyde functionality allows for conjugation reactions, useful in bioconjugation and prodrug strategies.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including novel cyclization and cross-coupling reactions.

Basic Information

Product Name	2-Amino-5-Pyrimidinecarboxyaldehyde
CAS No.	120747-84-4
Molecular Formula	C5H5N3O
Molecular Weight	123.11 g/mol
Synonyms	5-Formylpyrimidin-2-amine; 2-Amino-5-formylpyrimidine; 5-Pyrimidinecarboxaldehyde, 2-amino-; 2-Aminopyrimidine-5-carbaldehyde; 2-Amino-5-pyrimidinecarboxaldehyde; 2-Aminopyrimidine-5-carboxaldehyde; 5-Formyl-2-aminopyrimidine; 2-Amino-5-pyrimidine aldehyde
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Pyrimidinecarboxyaldehyde is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and propensity to be easily oxidized (store under inert atmosphere), it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to air and moisture during use.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.