Description

Pyrimidine, 5-(1-Fluoroethyl)-2-(Methylthio)- (9Ci) is a specialized fluorinated pyrimidine derivative, a key structural motif in medicinal chemistry and advanced material science. This compound matters as a versatile and high-value chemical building block for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D and process development teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate unique fluorine-containing heterocycles into their molecular designs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly in oncology and antiviral research, leveraging the biological activity of the pyrimidine core and the metabolic stability imparted by the fluorine atom.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorinated pyrimidine structure can enhance target binding and environmental persistence.
• Chemical Research & Development: Acts as a valuable scaffold for medicinal chemists exploring structure-activity relationships (SAR) and for creating focused libraries for high-throughput screening.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials, ligands for catalysis, or other specialty chemicals requiring a functionalized heterocyclic system.

Basic Information

Product Name	Pyrimidine, 5-(1-Fluoroethyl)-2-(Methylthio)- (9Ci)
CAS No.	120717-49-9
Molecular Formula	C7H9FN2S
Molecular Weight	172.22 g/mol
Synonyms	5-(1-Fluoroethyl)-2-(methylthio)pyrimidine; 2-(Methylthio)-5-(1-fluoroethyl)pyrimidine; 5-(1-Fluoroethyl)-2-methylsulfanylpyrimidine; 2-Methylsulfanyl-5-(1-fluoroethyl)pyrimidine; 120717-49-9; Pyrimidine, 2-(methylthio)-5-(1-fluoroethyl)-; SCHEMBL23850027
EINECS	Contact for details

Quality Control

Every batch of Pyrimidine, 5-(1-Fluoroethyl)-2-(Methylthio)- (9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for critical R&D and scale-up processes. Certificates of Analysis (COA) detailing specifications such as purity (by HPLC), identity (by NMR/IR), and impurity profiles are available upon request and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.