Description

Cryptdin CAS NO 120668-29-3 is a synthetic antimicrobial peptide (AMP) analog, designed to mimic the structure and function of natural cryptdins found in the intestinal Paneth cells. This compound is valued for its potent and broad-spectrum activity against bacteria, fungi, and certain enveloped viruses, making it a critical research tool and a candidate for therapeutic development. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for studying innate immunity, developing novel anti-infective agents, and exploring applications in wound healing and microbiome modulation.

Application

• Antimicrobial Research: Used as a reference standard and active agent in studies investigating the mechanisms of host defense peptides and their interactions with microbial membranes.
• Pharmaceutical Development: Serves as a lead compound or a structural template for the design of new peptide-based antibiotics and antifungal drugs.
• Biomaterial Coating: Incorporated into medical device coatings, wound dressings, and implant surfaces to impart antimicrobial properties and prevent biofilm formation.
• Immunology Studies: Employed to explore the role of Paneth cells and cryptdins in intestinal immunity, inflammatory bowel disease, and gut homeostasis.
• Veterinary Medicine: Investigated for potential use as an alternative to conventional antibiotics in animal health, targeting gastrointestinal pathogens.
• Cosmeceutical Formulations: Explored for use in topical skincare products aimed at managing acne and other skin conditions due to its antimicrobial and anti-inflammatory potential.

Basic Information

Product Name	Cryptdin
CAS No.	120668-29-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cryptdin-1; Cryptdin 1; Mouse cryptdin-1; α-Defensin-related cryptdin peptide; Paneth cell antimicrobial peptide; Defensin, cryptdin; Intestinal defensin
EINECS	Contact for details

Quality Control

Our Cryptdin is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, allow the vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Biological Activity	Assay-dependent; COA provided

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.