Description

4-Phosphono-Dl-Phenylalanine is a synthetic, phosphonated derivative of the amino acid phenylalanine, serving as a key building block in advanced chemical synthesis. This compound is valued for its ability to introduce a stable phosphonate moiety, which can mimic phosphate groups in biological systems and enhance metal-binding properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing enzyme inhibitors, prodrugs, and novel materials.

Application

• Pharmaceutical Intermediate: Used in the research and synthesis of novel drug candidates, particularly enzyme inhibitors targeting metabolic pathways.
• Agrochemical Research: Serves as a precursor for developing herbicides or plant growth regulators that utilize phosphonate chemistry.
• Bioconjugation & Probe Development: Acts as a linker or functional group for creating bioconjugates, imaging probes, or diagnostic agents due to its phosphonate group.
• Material Science: Employed in the synthesis of functionalized polymers, metal-organic frameworks (MOFs), or surface coatings where phosphonate groups provide chelation and stability.
• Biochemical Research: Used as a substrate analog or inhibitor in enzymatic studies to investigate phosphate-binding sites and mechanisms.
• Peptide Mimetics: Incorporated into peptide sequences to create phosphonopeptide analogs with enhanced stability and biological activity.

Basic Information

Product Name	4-Phosphono-Dl-Phenylalanine
CAS No.	120667-22-3
Molecular Formula	C9H12NO6P
Molecular Weight	261.17 g/mol
Synonyms	DL-4-Phosphonophenylalanine; (RS)-2-Amino-3-(4-phosphonophenyl)propanoic acid; Phenylalanine, 4-phosphono-, DL-; 4-Phosphono-DL-phenylalanine; Fosfonophenylalanine; 4-PPA; 4-Phosphono-DL-Phe; 2-Amino-3-(4-phosphonophenyl)propionic acid
EINECS	Contact for details

Quality Control

Our 4-Phosphono-Dl-Phenylalanine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-purity research-grade standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.