Description

4-Phosphonomethyl-D-Phenylalanine is a specialized, non-proteinogenic amino acid derivative featuring a phosphonomethyl group. This compound is of significant interest in pharmaceutical research and development, particularly as a key intermediate or building block for novel therapeutics. Its unique structure makes it valuable for scientists and manufacturers in the pharmaceutical and biotechnology sectors who are developing targeted drugs, enzyme inhibitors, or advanced peptide-based compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Enzyme Inhibitor Research: Used in biochemical research to study and develop inhibitors for specific enzymes, leveraging its phosphonate moiety.
• Peptidomimetic Development: Acts as a modified amino acid in the design and synthesis of peptidomimetics, which are stable compounds that mimic peptides.
• Chemical Biology Probes: Utilized in the creation of molecular probes to investigate biological pathways and protein functions.
• Preclinical Drug Development: Employed in early-stage drug discovery for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	4-Phosphonomethyl-D-Phenylalanine
CAS No.	120667-17-6
Molecular Formula	C10H14NO5P
Molecular Weight	259.20 g/mol
Synonyms	(R)-2-Amino-3-[4-(phosphonomethyl)phenyl]propanoic acid; D-4-Phosphonomethylphenylalanine; (R)-4-(Phosphonomethyl)phenylalanine; Pmp(D); D-Pmp; 4-(Phosphonomethyl)-D-phenylalanine; (2R)-2-Amino-3-[4-(phosphonomethyl)phenyl]propanoic acid; D-4-Carboxymethylphenylalanine (common misnomer)
EINECS	Contact for details

Quality Control

Our 4-Phosphonomethyl-D-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Optical Rotation	Specific range provided on COA
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.