Description

Pyrimido[4,5-D]Pyrimidin-2(1H)-One (6Ci) is a high-purity heterocyclic organic compound serving as a critical advanced intermediate in pharmaceutical research and development. Its fused pyrimidine core structure makes it a valuable building block for synthesizing novel active pharmaceutical ingredients (APIs) and complex molecular scaffolds. This compound is primarily utilized by medicinal chemists and R&D departments in the pharmaceutical, agrochemical, and fine chemical industries for lead optimization and the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Used in lead compound optimization and structure-activity relationship (SAR) studies due to its versatile heterocyclic core.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new pesticides and herbicides.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Biochemical Tool Compound: Potential use in developing probes for studying enzymatic and biological pathways.
• Academic & Institutional R&D: Used in universities and research institutes for fundamental organic chemistry and drug discovery projects.

Basic Information

Product Name	Pyrimido[4,5-D]Pyrimidin-2(1H)-One (6Ci)
CAS No.	120614-17-7
Molecular Formula	C6H4N4O
Molecular Weight	148.12 g/mol
Synonyms	1H-Pyrimido[4,5-d]pyrimidin-2-one; Pyrimido[4,5-d]pyrimidin-2(1H)-one; 2-Hydroxypyrimido[4,5-d]pyrimidine; 1,3-Diazinopyrimidin-2-ol; 6CI Compound; 6CI Numbered Compound; 120614-17-7 (CAS); Pyrimidopyrimidinone derivative
EINECS	Contact for details

Quality Control

Our Pyrimido[4,5-D]Pyrimidin-2(1H)-One (6Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.