Description

Proline, 5-Thioxo- (9Ci) is a specialized heterocyclic organic compound featuring a thioxo modification on the proline scaffold. This structural motif is of significant interest in advanced organic synthesis and pharmaceutical research, serving as a key building block for novel molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications requiring precise molecular modification.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or receptor modulation.
• Peptidomimetic Research: Used to introduce conformational constraints and novel bioisosteric elements into peptide analogs to enhance stability and biological activity.
• Agrochemical Synthesis: Serves as a building block for developing new active ingredients with potential herbicidal or fungicidal properties.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for studying enzyme function and metabolic pathways.
• Ligand Development: Utilized in medicinal chemistry for creating specialized ligands for metal coordination or as scaffolds for combinatorial chemistry libraries.
• Academic & Institutional Research: A valuable reagent for fundamental studies in organic chemistry, heterocyclic chemistry, and bioorganic chemistry.

Basic Information

Product Name	Proline, 5-Thioxo- (9Ci)
CAS No.	120610-89-1
Molecular Formula	C5H7NO2S
Molecular Weight	145.18 g/mol
Synonyms	5-Thioxoproline; 2-Pyrrolidinecarboxylic acid, 5-thioxo-; 5-Thioxo-DL-proline; 5-Thioxoprolin; Thiazolidine-4-carboxylic acid, 2-oxo-; 5-Thioxo-2-pyrrolidinecarboxylic acid; DL-5-Thioxoproline; 5-Thioxoproline (9CI)
EINECS	Contact for details

Quality Control

Our Proline, 5-Thioxo- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, related substances, and residual solvents, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.