Description

Acetamide, n-[6-Amino-1,2,3,4-Tetrahydro-1,3-Bis(2-Methylpropyl)-2,4-Dioxo-5-Pyrimidinyl]- is a specialized pyrimidine derivative with a unique acetamide substitution, serving as a critical high-purity building block in advanced organic synthesis. Its molecular structure makes it valuable for constructing complex heterocyclic frameworks, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development teams in the life sciences sector seeking to develop novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel therapeutic agents, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe Synthesis: Employed in the creation of specialized molecular probes for studying biological mechanisms and target identification.
• Advanced Organic Synthesis: Serves as a sophisticated building block for constructing complex, multi-functional heterocyclic compounds in academic and industrial R&D settings.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant scale for potential API manufacturing.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Acetamide, n-[6-Amino-1,2,3,4-Tetrahydro-1,3-Bis(2-Methylpropyl)-2,4-Dioxo-5-Pyrimidinyl]-
CAS No.	120562-83-6
Molecular Formula	C14H24N4O3
Molecular Weight	296.37 g/mol
Synonyms	N-(6-Amino-1,3-bis(isobutyl)-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)acetamide; 5-Acetamido-6-amino-1,3-diisobutyluracil; 6-Amino-1,3-diisobutyl-5-acetylaminouracil; 1,3-Diisobutyl-5-acetylamino-6-aminouracil; Acetamide, N-[6-amino-1,2,3,4-tetrahydro-1,3-bis(2-methylpropyl)-2,4-dioxo-5-pyrimidinyl]- (9CI)
EINECS	Contact for details

Quality Control

Our Acetamide, n-[6-Amino-1,2,3,4-Tetrahydro-1,3-Bis(2-Methylpropyl)-2,4-Dioxo-5-Pyrimidinyl]- is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all test results are provided and available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption. Recommended long-term storage temperature is between 2°C and 8°C (refrigerated). For prolonged storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.