Description

Biotinyl-Gly-Gly-Oh CAS NO 120447-60-1 is a high-purity, synthetic peptide derivative of biotin, designed for advanced biochemical and pharmaceutical research. This compound serves as a critical intermediate and building block for the synthesis of biotinylated probes, linkers, and conjugates, enabling precise biological targeting and detection. It is essential for researchers and manufacturers in the fields of proteomics, diagnostics, and drug discovery who require reliable, high-quality reagents for labeling and assay development.

Application

• Bioconjugation & Probe Synthesis: A key precursor for creating biotin-labeled peptides, proteins, and antibodies used in immunoassays (ELISA, Western Blot) and diagnostic kits.
• Drug Discovery & Development: Used as a specialized intermediate in the synthesis of targeted therapeutic agents and molecular imaging probes.
• Affinity Chromatography: Employed in the preparation of affinity resins and columns for the purification and isolation of biomolecules.
• Cell Biology & Proteomics Research: Facilitates the study of protein-protein interactions, cellular localization, and signal transduction pathways via biotin-streptavidin technology.
• Diagnostic Reagent Manufacturing: Integral to the production of high-sensitivity diagnostic components for clinical and research laboratories.
• Chemical Biology Tool Development: Serves as a versatile scaffold for developing novel chemical tools to study enzymatic activity and metabolic pathways.

Basic Information

Product Name	Biotinyl-Gly-Gly-Oh
CAS No.	120447-60-1
Molecular Formula	C14H22N4O5S
Molecular Weight	358.41 g/mol
Synonyms	Biotinyl-Gly-Gly; Biotin-Gly-Gly-OH; N-Biotinyl-glycylglycine; Glycylglycine, N-biotinyl-; 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-(2-amino-2-oxoethyl)pentanamide; Biotin-Gly-Gly; Biotinyl diglycine
EINECS	Contact for details

Quality Control

Our Biotinyl-Gly-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and comprehensive impurity profiling. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and cGMP-grade standards for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep container tightly sealed in a desiccated environment after opening.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.