Description

Deramciclane is a high-purity pharmaceutical intermediate and research chemical with significant importance in the development of novel therapeutic agents. Its primary value lies in its role as a key synthetic building block for advanced pharmacological research, particularly in the central nervous system (CNS) domain. This compound is essential for pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of advanced active pharmaceutical ingredients (APIs) targeting neurological pathways.
• Medicinal Chemistry Research: Used as a core scaffold or reference standard in structure-activity relationship (SAR) studies for CNS drug discovery.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in API manufacturing.
• Preclinical Development: Employed in the formulation of compounds for pharmacological profiling and early-stage toxicology studies.
• Academic Research: Utilized in university and institutional labs for studying receptor binding and biochemical mechanisms.
• Contract Synthesis: Supplied to CROs and CMOs for custom synthesis projects and scale-up process development.

Basic Information

Product Name	Deramciclane
CAS No.	120444-72-6
Molecular Formula	C22H25NO2
Molecular Weight	335.44 g/mol
Synonyms	EGIS-5645; 1-[2-(4-(3-Chlorophenyl)piperazin-1-yl)ethyl]-3,3-diphenylpyrrolidin-2-one; 3,3-Diphenyl-1-[2-[4-(3-chlorophenyl)-1-piperazinyl]ethyl]-2-pyrrolidinone; Deramciclane fumarate (salt form); Fumaric acid deramciclane salt
EINECS	Contact for details

Quality Control

Our Deramciclane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent control of residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.