Description

4-(Trifluoromethoxy)-3-(Trifluoromethyl)Phenol is a high-purity fluorinated phenolic compound, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique electronic and steric properties imparted by the trifluoromethoxy and trifluoromethyl substituents, which are essential for modulating the biological activity and physical characteristics of target molecules. This compound is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system, metabolic disorders, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity, metabolic stability, and binding affinity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways and creating compound libraries for high-throughput screening.
• Ligand and Catalyst Development: Utilized to construct sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-(Trifluoromethoxy)-3-(Trifluoromethyl)Phenol
CAS No.	120355-08-0
Molecular Formula	C9H4F6O2
Molecular Weight	258.12 g/mol
Synonyms	3-(Trifluoromethyl)-4-(trifluoromethoxy)phenol; 4-(Trifluoromethoxy)-3-(trifluoromethyl)phenol; Phenol, 4-(trifluoromethoxy)-3-(trifluoromethyl)-; 3-Trifluoromethyl-4-trifluoromethoxyphenol; 4-Trifluoromethoxy-3-trifluoromethylphenol; 120355-08-0; 4-(Trifluoromethoxy)-alpha,alpha,alpha,3-tetrafluoro-m-cresol
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)-3-(Trifluoromethyl)Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support compliance with relevant regulatory frameworks, including REACH and TSCA.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. The compound may be moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.