Description

2-(2-Fluorophenoxy)-1-Ethanamine is a specialized fluorinated aromatic amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the fluorine atom and phenoxy-ethylamine moiety are crucial for modulating biological activity and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific fluorinated motifs into target molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances efficacy and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for advanced polymers, coatings, and liquid crystals with tailored properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up services for clients requiring fluorinated aromatic amines.

Basic Information

Product Name	2-(2-Fluorophenoxy)-1-Ethanamine
CAS No.	120351-90-8
Molecular Formula	C8H10FNO
Molecular Weight	155.17 g/mol
Synonyms	2-(2-Fluorophenoxy)ethanamine; 1-Amino-2-(2-fluorophenoxy)ethane; 2-Fluorophenoxyethylamine; N-(2-Fluorophenoxy)ethylamine; 2-(2-Fluorophenoxy)ethylamine; β-Aminoethyl 2-fluorophenyl ether; 2-Fluoro-β-phenoxyethylamine; Ethanamine, 2-(2-fluorophenoxy)-
EINECS	Contact for details

Quality Control

Our 2-(2-Fluorophenoxy)-1-Ethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.