Description

Vasopressin, n-Acetyl-Arg(8)- is a synthetic, acetylated analog of the neurohypophysial hormone arginine vasopressin. This modification enhances its stability and alters its receptor binding profile, making it a valuable research tool for studying vasopressinergic systems. It is primarily utilized by pharmaceutical researchers and life science companies engaged in neuroendocrine and cardiovascular research. The compound is supplied with a guaranteed high level of purity to ensure reliable and reproducible experimental results.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating the structure-activity relationships (SAR) of vasopressin receptor ligands.
• Neurobiology Studies: Applied in in vitro and in vivo models to explore the role of vasopressin and its analogs in central nervous system functions, including social behavior, memory, and stress response.
• Biochemical Assay Development: Serves as a critical component in the development and validation of competitive binding assays (e.g., ELISA, RIA) and functional assays for vasopressin receptors (V1a, V1b, V2).
• Cardiovascular Research: Employed to study the vascular effects and potential therapeutic applications of modified vasopressin peptides on blood pressure and renal function.
• Peptide Chemistry & Drug Discovery: Acts as a key intermediate or model compound for designing novel peptide-based therapeutics with improved metabolic stability and selectivity.

Basic Information

Product Name	Vasopressin, n-Acetyl-Arg(8)-
CAS No.	120302-31-0
Molecular Formula	C48H68N14O13S2
Molecular Weight	1081.3 g/mol
Synonyms	[Arg8]-Vasopressin, N-Acetyl-; Acetyl-[Arg8]-vasopressin; N-Acetyl-8-arginine vasopressin; 1-(3-Mercaptopropanoic acid)-2-(O-methyl-L-tyrosine)-8-L-arginine-vasopressin, Nα-acetyl-; AVP analog; [Arg8]-AVP, N-Acetyl-; Desamino-[Arg8]-vasopressin, N-Acetyl- (related form)
EINECS	Contact for details

Quality Control

Our Vasopressin, n-Acetyl-Arg(8)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). A detailed Certificate of Analysis (COA) documenting the results is provided with every shipment to ensure traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content (AAA)	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.