Description

Lhrh, n-Ac-2-Nal(1)-4-Cl-Phe(2)-Trp(3)-Hci(6)-Alanh2(10)- CAS NO 120287-83-4 is a synthetic peptide analog of Luteinizing Hormone-Releasing Hormone (LHRH), specifically engineered with key amino acid substitutions to modulate its biological activity and stability. This high-purity compound is critical for advanced research and development in endocrinology and oncology, serving as a valuable tool for studying hormone-dependent pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the development of novel LHRH-based therapeutics for hormone-sensitive conditions.
• Endocrinology Studies: Used in laboratory research to investigate the structure-activity relationships (SAR) of LHRH analogs and their interaction with receptors.
• Oncology Research: Employed in preclinical studies targeting hormone-dependent cancers, such as prostate and breast cancer, to evaluate the efficacy of new treatment strategies.
• Biochemical Assay Development: Serves as a critical component in the development and validation of high-throughput screening (HTS) assays and diagnostic kits.
• Peptide Chemistry & Synthesis: Used as a building block or model compound for studying advanced peptide synthesis, modification, and purification techniques.
• Academic & Institutional Research: Provides a reliable research chemical for universities and government labs conducting fundamental studies in reproductive biology and peptide pharmacology.

Basic Information

Product Name	Lhrh, n-Ac-2-Nal(1)-4-Cl-Phe(2)-Trp(3)-Hci(6)-Alanh2(10)- CAS NO 120287-83-4
CAS No.	120287-83-4
Molecular Formula	C64H83ClN16O12
Molecular Weight	1287.9 g/mol
Synonyms	Ac-D-2-Nal-4-Cl-D-Phe-D-3-Pal-Ser-Tyr-D-Hci-Leu-Arg-Pro-D-Ala-NH2; LHRH Antagonist Analog; Gonadotropin-Releasing Hormone (GnRH) Antagonist; [Ac-D-2-Nal1, D-4-Cl-Phe2, D-3-Pal3, Arg5, D-Hci6, D-Ala10]-LHRH; Cetrorelix Acetate Related Compound; Synthetic LHRH Analog; Peptide LHRH Antagonist
EINECS	Contact for details

Quality Control

Our Lhrh analog is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We adhere to relevant guidelines for the production of research-grade peptides.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For extended storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 70.0%
Acetate Content (HPLC)	5.0% - 12.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.