Description

Aldosterone Secretion Inhibiting Factor (1-35) (Bovine) is a specific bioactive peptide fragment derived from bovine origin. This compound is of significant interest for its role in modulating the renin-angiotensin-aldosterone system (RAAS), a key hormonal pathway regulating blood pressure and electrolyte balance. It is primarily utilized by researchers in endocrinology, cardiovascular physiology, and pharmaceutical development for investigative and diagnostic applications.

Application

• Biomedical Research: Used as a critical tool in studying the mechanisms of aldosterone synthesis and secretion in adrenal cell cultures and tissue models.
• Endocrine System Studies: Applied in experiments to understand feedback inhibition within the renin-angiotensin-aldosterone system (RAAS).
• Cardiovascular Research: Investigated for its potential effects on blood pressure regulation and its interaction with other regulatory peptides.
• Pharmaceutical Development: Serves as a reference standard or biochemical reagent in the screening and development of novel therapeutic agents targeting hypertension and heart failure.
• Diagnostic Assay Development: May be employed in the development and calibration of immunoassays or other analytical methods for measuring related hormones.

Basic Information

Product Name	Aldosterone Secretion Inhibiting Factor (1-35) (Bovine)
CAS No.	120249-06-1
Molecular Formula	C175H282N52O51S
Molecular Weight	~3950.5 g/mol
Synonyms	Aldosterone Secretion Inhibiting Factor (1-35), Bovine; ASIF (1-35); Aldosterone Inhibitory Factor; Aldosterone Secretion Inhibitor; ASIF Fragment 1-35; Bovine Adrenal Peptide Fragment; RAAS Inhibitory Peptide; Proadrenomedullin N-terminal 20 peptide (PAMP) related fragment; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Aldosterone Secretion Inhibiting Factor (1-35) (Bovine) is produced and handled under strict quality protocols suitable for research applications. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity by HPLC, peptide content, and other relevant specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, acetic acid, or DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.