Description

2-Chlorophenylalanine Hydrochloride is a halogenated derivative of the essential amino acid phenylalanine, serving as a key chiral building block and intermediate in advanced organic synthesis. Its value lies in providing a structurally defined scaffold for the development of novel pharmaceuticals and bioactive compounds. This product is essential for research and production in pharmaceutical chemistry, particularly for medicinal chemists and process development scientists working on targeted therapies.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological and metabolic pathways.
• Peptide Synthesis: Used as a modified amino acid residue in the solid-phase and solution-phase synthesis of specialized peptides and peptidomimetics.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and as a standard in analytical method development for amino acid analysis.
• Agrochemical Development: Acts as a building block for creating new chiral compounds with potential herbicidal or fungicidal activity.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective reactions to construct complex molecular architectures.

Basic Information

Product Name	2-Chlorophenylalanine Hydrochloride
CAS No.	120108-63-6
Molecular Formula	C9H11ClNO2 • HCl
Molecular Weight	250.10 g/mol
Synonyms	(2-Chloro-DL-phenylalanine) hydrochloride; DL-2-Chlorophenylalanine hydrochloride; 2-Chloro-α-aminohydrocinnamic acid hydrochloride; (±)-2-Chlorophenylalanine HCl; α-Amino-2-chlorobenzene propanoic acid hydrochloride; 2-Cl-Phe-OH • HCl; 2-Chlorophenylalanine HCl salt
EINECS	Contact for details

Quality Control

Our 2-Chlorophenylalanine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.