Description

3-Chloro- Phenylalanine, Hydrochloride is a halogenated derivative of the essential amino acid phenylalanine, modified as a hydrochloride salt for enhanced stability and handling. This compound serves as a crucial chiral building block and intermediate in the synthesis of more complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers developing novel therapeutic agents, including enzyme inhibitors and peptide-based drugs.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for metabolic and neurological targets.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a chlorinated phenylalanine residue, altering the peptide's properties and bioactivity.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies to investigate amino acid metabolism and related pathways.
• Proteomics & Labeling: Potential use as a modified amino acid in metabolic labeling strategies for mass spectrometry-based proteomic analysis.
• Agrochemical Research: Intermediate in the development of novel herbicides or plant growth regulators that mimic or interfere with amino acid functions.

Basic Information

Product Name	3-Chloro- Phenylalanine, Hydrochloride
CAS No.	120108-62-5
Molecular Formula	C9H11Cl2NO2
Molecular Weight	244.10 g/mol
Synonyms	(S)-2-Amino-3-(3-chlorophenyl)propanoic acid hydrochloride; L-3-Chlorophenylalanine hydrochloride; 3-Chloro-L-phenylalanine HCl; 3-Cl-Phe-OH·HCl; (2S)-2-Azaniumyl-3-(3-chlorophenyl)propanoate chloride; 3-Chlorophenylalanine HCl salt; 3-CPhe-HCl
EINECS	Contact for details

Quality Control

Our 3-Chloro- Phenylalanine, Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.