Description

H-D-Ile-Asp-Oh CAS NO 120067-35-8 is a high-purity, protected dipeptide building block, specifically the aspartic acid derivative with an isoleucine residue. This compound is a critical intermediate in the synthesis of complex peptides and peptidomimetics, offering precise control over molecular structure and stereochemistry. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and fine chemical manufacturers engaged in the development of therapeutic peptides, diagnostic agents, and biochemical research tools.

Application

• Pharmaceutical Intermediate: Key building block for the solid-phase and solution-phase synthesis of novel therapeutic peptides targeting metabolic disorders, oncology, and infectious diseases.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and for probing protein-protein interactions due to its specific amino acid sequence.
• Peptidomimetic Development: Serves as a core structure for designing and synthesizing non-natural peptide analogs with enhanced stability and bioavailability.
• Diagnostic Reagent Synthesis: Incorporated into the production of labeled peptides for use in immunoassays, imaging probes, and other diagnostic applications.
• Cosmeceutical Actives: Potential ingredient in the research and development of advanced bioactive peptides for skincare formulations.

Basic Information

Product Name	H-D-Ile-Asp-Oh
CAS No.	120067-35-8
Molecular Formula	C10H18N2O5
Molecular Weight	246.26 g/mol
Synonyms	H-D-Ile-Asp-OH; H-D-Isoleucyl-L-aspartic acid; D-Isoleucyl-L-aspartic acid; (2S)-2-[[(2R,3R)-2-amino-3-methylpentanoyl]amino]butanedioic acid; Aspartic acid, N-(D-isoleucyl)-; Ile-Asp; D-Ile-L-Asp-OH; Protected Ile-Asp dipeptide
EINECS	Contact for details

Quality Control

Our H-D-Ile-Asp-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via MS and NMR. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Keep the container sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.