Description

(E)-5-(2-Carboxyvinyl)-2,4-Dimethoxypyrimidine is a high-purity pyrimidine derivative characterized by its vinyl carboxylic acid functionality. This compound serves as a critical building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by fine chemical manufacturers and R&D laboratories engaged in the creation of novel active pharmaceutical ingredients (APIs) and other advanced organic materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of nucleoside analogs, antiviral agents, and other therapeutic compounds.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, cycloadditions, and other advanced transformations to construct complex heterocyclic systems.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Potential monomer or functionalizing agent for creating specialized polymers with tailored properties.
• Academic & Industrial R&D: Used in medicinal chemistry programs and process development for scale-up synthesis.

Basic Information

Product Name	(E)-5-(2-Carboxyvinyl)-2,4-Dimethoxypyrimidine
CAS No.	119923-27-2
Molecular Formula	C9H10N2O4
Molecular Weight	210.19 g/mol
Synonyms	5-[(1E)-3-Carboxy-1-propen-1-yl]-2,4-dimethoxypyrimidine; (E)-5-(2-Carboxyethenyl)-2,4-dimethoxypyrimidine; 2,4-Dimethoxy-5-[(E)-2-carboxyvinyl]pyrimidine; 5-(2-Carboxyvinyl)-2,4-dimethoxypyrimidine (E-isomer); trans-5-(2-Carboxyvinyl)-2,4-dimethoxypyrimidine; Pyrimidine, 5-(2-carboxyethenyl)-2,4-dimethoxy-, (E)-; A potential pharmaceutical intermediate code name (varies by manufacturer).
EINECS	Contact for details

Quality Control

Our (E)-5-(2-Carboxyvinyl)-2,4-Dimethoxypyrimidine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and should be handled with appropriate precautions for chemicals soluble in strong acids/organic solvents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.