Description

Grepafloxacin CAS NO 119914-60-2 is a synthetic broad-spectrum fluoroquinolone antibiotic agent. It is valued for its potent activity against a wide range of Gram-positive and Gram-negative bacteria, including respiratory pathogens. This compound is primarily utilized in pharmaceutical research and development for the synthesis of antibacterial agents. Its mechanism of action involves inhibition of bacterial DNA gyrase and topoisomerase IV.

Application

• Pharmaceutical Intermediate: Key raw material in the synthesis of advanced antibacterial drug formulations.
• Antibacterial Research: Used as a reference standard and active component in microbiological and pharmacological studies.
• Veterinary Medicine Development: Investigated for potential applications in treating bacterial infections in animals.
• Clinical Research Compound: Serves as a model compound for studying fluoroquinolone structure-activity relationships and resistance mechanisms.

Basic Information

Product Name	Grepafloxacin
CAS No.	119914-60-2
Molecular Formula	C19H22FN3O3
Molecular Weight	359.40 g/mol
Synonyms	OPC-17116; Grepafloxacin Hydrochloride (salt form); (±)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid; OPC17116; BMS-284756
EINECS	Contact for details

Quality Control

Our Grepafloxacin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity and related substances, identity confirmation by spectroscopic methods, and residual solvent analysis. Certificates of Analysis (COA) detailing all test results are available upon request to ensure full transparency and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.