Description

Poly (Arginyl-Glycyl-Aspartic Acid) is a synthetic polypeptide designed to mimic the cell-adhesive properties of the natural RGD (Arg-Gly-Asp) sequence found in extracellular matrix proteins. This compound is critical for applications requiring precise control over cell-material interactions, offering a powerful tool for surface functionalization. It is primarily utilized by researchers and manufacturers in the biomedical, tissue engineering, and advanced biomaterials sectors to promote specific cellular adhesion and enhance biocompatibility.

Application

• Biomedical Research: As a key component in studies of cell adhesion, migration, and signaling pathways.
• Tissue Engineering Scaffolds: Coating material for synthetic or natural polymer scaffolds to improve cell attachment and proliferation.
• Medical Device Coatings: Surface modification of implants (e.g., stents, bone grafts) to enhance biocompatibility and integration with host tissue.
• Diagnostic Assays: Functionalization of biosensor surfaces and microarray chips for cell-based detection systems.
• Drug Delivery Systems: Incorporation into nanoparticle or hydrogel carriers to target specific cell types via integrin receptor recognition.
• Basic Cell Culture: Coating cell culture plates and dishes to create a more physiologically relevant adhesive substrate for sensitive cell lines.

Basic Information

Product Name	Poly (Arginyl-Glycyl-Aspartic Acid)
CAS No.	119865-10-0
Molecular Formula	(C15H26N8O6)n
Molecular Weight	Variable (Polymer)
Synonyms	Poly(RGD); RGD Peptide Polymer; Poly(Arg-Gly-Asp); Polyarginylglycylaspartic Acid; cRGD Peptide Polymer; Adhesive Peptide Polymer; Integrin-Binding Peptide Polymer; GRGDSP Polymer
EINECS	Contact for details

Quality Control

Our Poly (Arginyl-Glycyl-Aspartic Acid) is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including assessment of amino acid composition, sequence integrity, and molecular weight distribution, to ensure consistency and performance for research and biomedical applications. Certificates of Analysis (COA) detailing purity, endotoxin levels, and sterility (where applicable) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For extended storage of aliquoted solutions, use sterile, low-protein-binding containers.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Amino Acid Analysis	Conforms to theoretical composition
Water Content	≤ 5.0%
Endotoxin Level	< 1.0 EU/mg (for specific grades)
Solubility	Soluble in water or aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.