Description

Z-Ala-Trp-Oh CAS NO 119645-65-7 is a protected dipeptide derivative, specifically the benzyloxycarbonyl (Z) protected form of the alanine-tryptophan dipeptide with a free carboxylic acid. This compound is a crucial high-purity building block in peptide synthesis, offering precise control over sequence assembly. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers for developing novel therapeutic peptides and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled elongation of peptide chains in research and development.
• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in studies of enzyme-substrate interactions, receptor binding, and other structure-activity relationship (SAR) investigations.
• Custom Peptide Production: An essential raw material for CROs and CDMOs specializing in the manufacture of custom, non-standard peptides.
• Protecting Group Chemistry: Demonstrates the application of the Z (Cbz) protecting group, which is selectively removable under mild hydrogenation conditions.

Basic Information

Item	Details
Product Name	Z-Ala-Trp-Oh
CAS No.	119645-65-7
Molecular Formula	C24H25N3O5
Molecular Weight	435.48 g/mol
Synonyms	N-Cbz-L-Alanyl-L-Tryptophan; N-Carbobenzoxy-L-alanyl-L-tryptophan; Z-L-Ala-L-Trp-OH; Cbz-Ala-Trp-OH; Benzyloxycarbonyl-L-alanyl-L-tryptophan; Nα-[(Benzyloxy)carbonyl]-L-alanyl-L-tryptophan; N-CBZ-L-ALANYL-L-TRYPTOPHAN; L-Tryptophan, N-[(phenylmethoxy)carbonyl]-L-alanyl-
EINECS	Contact for details

Quality Control

Our Z-Ala-Trp-Oh is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	-20.0° to -25.0° (c=1 in DMF)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.