Description

Olprinone Hydrochloride is a selective phosphodiesterase III (PDE III) inhibitor used as a potent cardiotonic agent. Its primary value lies in providing inotropic support and vasodilation, making it a critical component in the development of treatments for acute heart failure. This high-purity compound is essential for pharmaceutical R&D, analytical reference standard preparation, and the manufacturing of active pharmaceutical ingredients (APIs).

Application

• Active Pharmaceutical Ingredient (API) in cardiotonic medications for acute heart failure.
• Pharmaceutical reference standard for quality control and analytical method development.
• Key intermediate in the research and synthesis of novel PDE III inhibitor derivatives.
• Biochemical research tool for studying cardiac muscle contractility and vascular smooth muscle relaxation.
• Use in preclinical and clinical studies to evaluate cardiovascular drug efficacy and safety profiles.

Basic Information

Product Name	Olprinone Hydrochloride
CAS No.	119615-63-3
Molecular Formula	C₁₄H₁₀N₄O•HCl
Molecular Weight	290.72 g/mol
Synonyms	1,2-Dihydro-5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-3-pyridinecarbonitrile hydrochloride; E-1020; Olprinone HCl; 6-Methyl-2-oxo-5-(imidazo[1,2-a]pyridin-6-yl)-1,2-dihydropyridine-3-carbonitrile hydrochloride
EINECS	Contact for details

Quality Control

Our Olprinone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation, to ensure it meets high-grade pharmaceutical standards. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5%
Single Maximum Impurity	≤0.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.