Description

(-)-Biperiden CAS NO 119542-35-7 is the levorotatory enantiomer of the anticholinergic agent Biperiden. This specific stereoisomer is of significant interest in advanced pharmaceutical research and development due to its targeted pharmacological profile. It is primarily utilized by pharmaceutical companies and research institutions engaged in the synthesis of novel therapeutics for central nervous system disorders. The compound's high stereochemical purity is critical for precise biological evaluation and process development.

Application

• Active Pharmaceutical Ingredient (API) intermediate for neurological medications.
• Reference standard in analytical method development and validation for chiral separation.
• Key starting material in the research and synthesis of enantiomerically pure anticholinergic agents.
• Pharmacological studies investigating subtype-specific muscarinic receptor antagonism.
• Process chemistry development for the scalable production of stereoselective drugs.
• Quality control laboratories for impurity profiling and identification.

Basic Information

Product Name	(-)-Biperiden
CAS No.	119542-35-7
Molecular Formula	C21H29NO
Molecular Weight	311.47 g/mol
Synonyms	(-)-Biperiden; (S)-Biperiden; Levo-Biperiden; (αS)-α-Bicyclo[2.2.1]hept-5-en-2-yl-α-phenyl-1-piperidinepropanol; 1-[(1S)-Bicyclo[2.2.1]hept-5-en-2-yl]-1-phenyl-3-(piperidin-1-yl)propan-1-ol; Akineton (Levo-isomer); Naphthylpiperidylpropanol derivative
EINECS	Contact for details

Quality Control

Our (-)-Biperiden is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and enantiomeric excess meet rigorous standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting results for key parameters including assay, chiral purity, and related substances. We support compliance with cGMP and ICH guidelines for pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.