Description

Hemoglobin F Granada is a specific variant of fetal hemoglobin (HbF) characterized by a point mutation. This compound is of significant interest in biochemical and hematological research for studying hemoglobinopathies and the regulation of fetal hemoglobin expression. It serves as a critical reference material and reagent for scientists and diagnostic manufacturers focused on sickle cell disease, β-thalassemia, and related genetic blood disorders.

Application

• Biochemical Research: Used as a purified standard in studies investigating the structure, function, and oxygen-binding properties of mutant fetal hemoglobins.
• Diagnostic Development: Acts as a key component in the calibration and validation of diagnostic assays and kits designed to detect and quantify specific hemoglobin variants.
• Therapeutic Research: Employed in preclinical research aimed at understanding and developing therapies that modulate hemoglobin switching, such as for sickle cell disease.
• Quality Control Reference: Serves as a high-purity reference standard for quality control in clinical laboratories and in the production of in-vitro diagnostic devices (IVDs).
• Hematology Studies: Utilized in experimental models to analyze the impact of specific hemoglobin mutations on red blood cell physiology and pathology.

Basic Information

Product Name	Hemoglobin F Granada
CAS No.	119467-95-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hb F Granada; Fetal Hemoglobin Granada; Hemoglobin F (Granada variant); γ-globin variant Granada; HbF Granada; Granada Hemoglobin F; Fetal Hb Granada
EINECS	Contact for details

Quality Control

Our Hemoglobin F Granada is produced and handled under stringent conditions to ensure batch-to-batch consistency and high purity, suitable for research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and relevant biochemical parameters. We adhere to rigorous internal quality standards to meet the exacting requirements of the life science and diagnostic industries.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (HPLC/Electrophoresis)	Conforms to standard for Hb F Granada
Purity (HPLC)	≥ 95%
Solubility	Soluble in appropriate aqueous buffers
Protein Content (UV-Vis)	Contact for details
Endotoxin Level	< 1.0 EU/mg (where specified)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.