Description

Cd4 Fragment 25-58 CAS NO 119112-09-3 is a synthetic peptide fragment corresponding to a specific region of the human CD4 protein, a critical receptor on T-helper cells. This high-purity peptide is essential for advanced biochemical and immunological research, serving as a key tool for studying protein-protein interactions, immune cell signaling, and antigen presentation. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic developers focused on immunology, autoimmune diseases, and novel therapeutic discovery.

Application

• Biochemical Research: Used as a reference standard or binding partner in studies of T-cell receptor (TCR) and Major Histocompatibility Complex (MHC) class II interactions.
• Immunoassay Development: Serves as a critical antigen or coating agent in the development of ELISA and other immunoassays for detecting antibodies or studying immune responses.
• Drug Discovery Screening: Employed in high-throughput screening (HTS) platforms to identify and characterize potential inhibitors or modulators of the CD4-mediated signaling pathway.
• Antigen-Specific Studies: Acts as a precise tool for investigating the molecular mechanisms of antigen presentation and T-cell activation in autoimmune and infectious disease models.
• Peptide Antibody Production: Used as an immunogen to generate specific polyclonal or monoclonal antibodies targeting the CD4 protein for diagnostic or therapeutic applications.
• Structural Biology: Provides a defined peptide sequence for X-ray crystallography, NMR spectroscopy, or computational modeling to elucidate three-dimensional protein structures.

Basic Information

Product Name	Cd4 Fragment 25-58
CAS No.	119112-09-3
Molecular Formula	C164H262N48O49S
Molecular Weight	3708.2 g/mol
Synonyms	CD4 (25-58) (human); T-cell surface glycoprotein CD4 (25-58); CD4 Peptide Fragment; CD4 Antigen Fragment; Leupeptin; HIV Receptor Fragment; T-cell Antigen T4/Leu-3 Fragment; L3T4 Fragment
EINECS	Contact for details

Quality Control

Every batch of Cd4 Fragment 25-58 is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are supported by a detailed Certificate of Analysis (COA) that includes data from multiple orthogonal methods. We adhere to relevant industry guidelines for peptide synthesis and can provide material suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	± 10% of theoretical
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.