Description

Poly(L-Glutamic Acid-L-Tyrosine) Sodium Salt is a synthetic, water-soluble polypeptide copolymer derived from the amino acids L-glutamic acid and L-tyrosine. This engineered biomaterial is valued for its biocompatibility, controlled biodegradability, and functional side chains that allow for chemical modification. It serves as a critical functional polymer in advanced biomedical research and pharmaceutical development, particularly for creating sophisticated drug delivery systems and biocompatible scaffolds. Key industries that utilize this specialty polymer include pharmaceutical R&D, biomedical engineering, and advanced material science.

Application

• Drug Delivery Systems: As a biodegradable carrier for controlled and targeted release of therapeutic agents, including anticancer drugs and proteins.
• Tissue Engineering Scaffolds: Used to fabricate three-dimensional, biocompatible matrices that support cell growth and tissue regeneration.
• Biomedical Hydrogels: A key component in the formulation of injectable or implantable hydrogels for wound healing and sustained-release applications.
• Conjugate Vaccine Adjuvants: Acts as a polymeric backbone for antigen conjugation to enhance immunogenicity and vaccine stability.
• Biomimetic Material Research: Serves as a model system for studying protein-polymer interactions and designing novel bio-inspired materials.
• Cosmetic & Dermatological Formulations: Employed in advanced skincare products for its film-forming and moisturizing properties.

Basic Information

Product Name	Poly(L-Glutamic Acid-L-Tyrosine) Sodium Salt
CAS No.	119039-70-2
Molecular Formula	(C5H7NO4·C9H9NO3)nxNa
Molecular Weight	Variable (Polymer)
Synonyms	Poly(L-Glu-L-Tyr) Sodium Salt; PGA-Tyr Copolymer Sodium Salt; Sodium Poly(glutamate-co-tyrosine); Poly(glutamic acid-tyrosine) sodium salt; L-Glutamic Acid-L-Tyrosine Copolymer Sodium Salt; PGA-PTyr; P(Glu-co-Tyr)Na; Glutamic Acid and Tyrosine Copolymer Sodium Salt
EINECS	Contact for details

Quality Control

Our Poly(L-Glutamic Acid-L-Tyrosine) Sodium Salt is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including determination of molecular weight distribution, copolymer composition ratio, residual solvent analysis, and endotoxin levels where applicable. A Certificate of Analysis (COA) documenting purity, identity, and key physical-chemical parameters is provided to ensure traceability and compliance with your research or GMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent moisture uptake and degradation. For long-term stability, consider storage under inert atmosphere or at refrigerated conditions (2-8°C).

Specification

Item	Specification
Appearance	White to off-white powder or fibrous solid
Identification (IR)	Conforms to structure
Assay (Content)	≥ 95.0% (on anhydrous basis)
Composition (Glu:Tyr Molar Ratio)	As per customer requirement (e.g., 4:1, 1:1)
Weight-Average Molecular Weight (Mw)	5 kDa - 500 kDa (Customizable)
Polydispersity Index (PDI)	≤ 2.0 (Typical)
Loss on Drying	≤ 5.0 %
Residual Solvents	Meets ICH guidelines
Endotoxin (if required)	< 0.25 EU/mg
pH (1% Solution)	6.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.