Description

n-Acetyl-S-(1,1,2,2-Tetrafluoroethyl)-1-Cysteine CAS NO 119018-04-1 is a specialized organofluorine derivative of cysteine, designed for advanced research and synthesis. This compound is a critical building block and analytical standard in the development of pharmaceuticals and agrochemicals, particularly for studying metabolism and creating novel bioactive molecules. It is essential for researchers and manufacturers in medicinal chemistry, toxicology, and the life sciences who require high-purity, well-characterized fluorinated intermediates.

Application

• Pharmaceutical Research & Development: Key intermediate in the synthesis of novel drug candidates, especially those incorporating fluorinated motifs for enhanced metabolic stability and bioavailability.
• Metabolite Identification & Toxicology Studies: Serves as a reference standard or synthetic precursor for characterizing and quantifying fluorinated metabolites in ADME (Absorption, Distribution, Metabolism, and Excretion) studies.
• Bioconjugation & Probe Development: Used in creating fluorescent or affinity probes for studying protein interactions and enzymatic activity due to its reactive thiol (cysteine) backbone.
• Agrochemical Synthesis: Building block for developing advanced pesticides and herbicides where the tetrafluoroethyl group can impart unique biological activity and environmental persistence profiles.
• Material Science: Potential monomer or modifier in the synthesis of specialty polymers with specific surface properties or chemical resistance.

Basic Information

Product Name	n-Acetyl-S-(1,1,2,2-Tetrafluoroethyl)-1-Cysteine
CAS No.	119018-04-1
Molecular Formula	C7H9F4NO3S
Molecular Weight	263.21 g/mol
Synonyms	N-Acetyl-S-(1,1,2,2-tetrafluoroethyl)-L-cysteine; N-Acetyl-S-(1,1,2,2-tetrafluoroethyl)cysteine; Acetylcysteine tetrafluoroethyl derivative; 2-(Acetylamino)-3-[[1,1,2,2-tetrafluoroethyl]sulfanyl]propanoic acid; S-(1,1,2,2-Tetrafluoroethyl)-N-acetyl-L-cysteine; TFE-NAC; Mercapturic acid derivative of 1,1,2,2-tetrafluoroethylating agents
EINECS	Contact for details

Quality Control

Our n-Acetyl-S-(1,1,2,2-Tetrafluoroethyl)-1-Cysteine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.