Description

4-Chloro-6-(Methylsulfanyl)-2-Phenyl-5-Pyrimidinecarbonitrile is a high-value pyrimidine derivative building block used in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, enabling the construction of complex heterocyclic scaffolds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require a functionalized pyrimidine core.
• Material Science Research: Serves as a precursor for creating organic electronic materials and ligands for metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Industrial R&D: Employed in research laboratories for methodological development and exploring new chemical reactions involving halogenated and sulfur-containing heterocycles.

Basic Information

Product Name	4-Chloro-6-(Methylsulfanyl)-2-Phenyl-5-Pyrimidinecarbonitrile
CAS No.	118996-61-5
Molecular Formula	C12H8ClN3S
Molecular Weight	261.73 g/mol
Synonyms	4-Chloro-6-(methylthio)-2-phenyl-5-pyrimidinecarbonitrile; 5-Pyrimidinecarbonitrile, 4-chloro-6-(methylthio)-2-phenyl-; 4-Chloro-6-methylsulfanyl-2-phenyl-pyrimidine-5-carbonitrile; 2-Phenyl-4-chloro-6-methylmercapto-5-cyanopyrimidine; 4-Chloro-6-methylthio-2-phenyl-5-cyanopyrimidine; 4-Chloro-6-(methylsulfanyl)-2-phenylpyrimidine-5-carbonitrile; 118996-61-5
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(Methylsulfanyl)-2-Phenyl-5-Pyrimidinecarbonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are provided for each lot to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.