Description

Atrial Natriuretic Peptide (1-29), Chicken is a synthetic polypeptide fragment corresponding to the biologically active sequence of the chicken-derived hormone. This compound is a critical research-grade biochemical tool for studying cardiovascular physiology, renal function, and natriuretic peptide receptor signaling pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in metabolic and cardiovascular disease research.

Application

• Cardiovascular Research: Used as a reference standard and active agent in studies investigating blood pressure regulation, vasodilation, and heart failure models.
• Renal Physiology Studies: Applied in research on sodium excretion (natriuresis), diuresis, and kidney function modulation.
• Receptor Binding Assays: Serves as a high-affinity ligand for characterizing and quantifying natriuretic peptide receptors (NPR-A, NPR-B).
• Biochemical Pathway Analysis: A key tool for elucidating the cGMP-mediated signaling cascades activated by natriuretic peptides.
• Pharmaceutical Development: Employed in preclinical studies for screening and developing novel therapeutics targeting hypertension and congestive heart failure.
• Cell Culture & In Vitro Studies: Used to stimulate cellular responses in cultured endothelial, renal, and cardiac cells for mechanistic studies.

Basic Information

Product Name	Atrial Natriuretic Peptide (1-29), Chicken
CAS No.	118691-45-5
Molecular Formula	C142H224N50O42S2
Molecular Weight	3164.7 g/mol
Synonyms	ANP (1-29), Chicken; Avian Atrial Natriuretic Peptide (1-29); Atriopeptin (1-29), Chicken; Cardionatrin (1-29), Chicken; rANP (1-29); H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH (Disulfide bridge: Cys7-Cys23); Chicken Heart Atrial Natriuretic Polypeptide Fragment 1-29
EINECS	Contact for details

Quality Control

Our Atrial Natriuretic Peptide (1-29), Chicken is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency for research applications. Each lot undergoes rigorous analytical testing including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Solubility	Soluble in water or aqueous acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.