Description

Atrial Natriuretic Peptide, Frog is a specific isoform of the natriuretic peptide hormone, identified by CAS No. 118691-43-3, derived from amphibian sources. This peptide is of significant value in comparative endocrinology and biomedical research for studying the evolution, structure, and function of the natriuretic peptide system. It is primarily needed by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on cardiovascular physiology, peptide hormone research, and the development of novel therapeutic agents.

Application

• Biomedical Research: Used as a reference standard in studies investigating the physiological roles and mechanisms of natriuretic peptides across different species.
• Pharmacological Studies: Employed in receptor binding assays and functional bioassays to characterize ANP receptor subtypes and signaling pathways.
• Comparative Endocrinology: Serves as a crucial tool for understanding the evolutionary biology and structural variance of cardiac hormones.
• Antibody Production & Immunoassays: Acts as an antigen for generating specific antibodies used in ELISA, RIA, and immunohistochemistry applications.
• Drug Discovery Screening: Utilized in high-throughput screening platforms to identify and evaluate potential modulators of the natriuretic peptide system.
• Academic Teaching: Provides a practical example for advanced courses in endocrinology, peptide chemistry, and molecular biology.

Basic Information

Product Name	Atrial Natriuretic Peptide, Frog
CAS No.	118691-43-3
Molecular Formula	C145H244N50O43S2 (Representative)
Molecular Weight	~3300 g/mol (Approximate)
Synonyms	Frog ANP; Rana catesbeiana Atrial Natriuretic Peptide; Cardionatrin; Atriopeptin; ANF (Atrial Natriuretic Factor); Auriculin; Atriopeptigen; rANP
EINECS	Contact for details

Quality Control

Our Atrial Natriuretic Peptide, Frog is produced and controlled under stringent conditions suitable for research use. Each batch undergoes rigorous analytical testing to ensure identity, purity, and biological activity. A comprehensive Certificate of Analysis (COA) is provided, detailing results for purity (by HPLC), peptide content, amino acid analysis, and mass spectrometry (MS) confirmation. We adhere to high standards of quality assurance to guarantee batch-to-batch consistency and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider storing under an inert atmosphere or in aliquots to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Complies with theoretical composition
Water Content (KF)	≤ 5.0%
Biological Activity	Determined by specific bioassay (e.g., cGMP accumulation assay)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.