Description

Butyloxycarbonyl-Lysinyl-Tryptophyl-Glycyl-Lysine is a protected tetrapeptide building block of significant interest in advanced pharmaceutical research and development. This compound is critical for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics, offering precise control over molecular structure. It is primarily utilized by research institutions, biotechnology firms, and pharmaceutical companies engaged in the discovery of novel therapeutic agents, including hormone analogs and targeted bioactive molecules. Its defined structure facilitates the study of structure-activity relationships (SAR) and the production of high-purity peptide intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex therapeutic peptides and peptidomimetic drugs.
• Biochemical Research: Used in academic and industrial R&D for studying peptide-protein interactions, enzyme substrates, and receptor binding assays.
• Hormone Analog Development: A critical precursor in the design and synthesis of analogs for hormones and growth factors.
• Solid-Phase Peptide Synthesis (SPPS): Employed as a protected fragment in Fmoc/t-Boc chemistry to construct longer peptide chains with high fidelity.
• Prodrug Synthesis: Utilized in the design of peptide-based prodrugs to enhance drug delivery, solubility, and targeting.
• Diagnostic Reagent Production: Acts as a component in the development of labeled peptides for diagnostic imaging and assay kits.

Basic Information

Product Name	Butyloxycarbonyl-Lysinyl-Tryptophyl-Glycyl-Lysine
CAS No.	118573-63-0
Molecular Formula	C34H52N8O8
Molecular Weight	700.83 g/mol
Synonyms	Boc-Lys-Trp-Gly-Lys; Boc-Lys(Boc)-Trp-Gly-Lys(Boc); t-Butyloxycarbonyl-L-lysyl-L-tryptophyl-glycyl-L-lysine; Nα-Boc-Lys(Nε-Boc)-Trp-Gly-Lys(Nε-Boc); (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoic acid; Tetrapeptide Boc-Lys-Trp-Gly-Lys; Protected Lys-Trp-Gly-Lys fragment; BOC-LYS-TRP-GLY-LYS-OH
EINECS	Contact for details

Quality Control

Our peptide building blocks are manufactured under strict quality management systems. Each batch of Butyloxycarbonyl-Lysinyl-Tryptophyl-Glycyl-Lysine undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and pre-clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, temperature-controlled environment. This product is hygroscopic (moisture-sensitive). For long-term storage, containers should be sealed under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Chiral Purity	≥ 99.0% (by chiral HPLC)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.