Description

Cyclo(L-Phenylalanyl-trans-4-Hydroxy-L-Proline) is a synthetic cyclic dipeptide, also known as a diketopiperazine (DKP), derived from the amino acids phenylalanine and hydroxyproline. This compound is of significant interest in pharmaceutical research and development due to its role as a key intermediate and scaffold for creating novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide chemistry, medicinal chemistry, and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of more complex peptide-based drugs and protease inhibitors.
• Medicinal Chemistry Research: Used as a privileged scaffold in structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Biochemical Tool Compound: Employed in enzymatic studies and as a reference standard in analytical method development for peptide analysis.
• Cosmeceutical Ingredient: Investigated for potential applications in anti-aging and skin repair formulations due to its peptide structure.

Basic Information

Product Name	Cyclo(L-Phenylalanyl-trans-4-Hydroxy-L-Proline)
CAS No.	118477-06-8
Molecular Formula	C14H16N2O3
Molecular Weight	260.29 g/mol
Synonyms	Cyclo(Phe-Hyp); Cyclo(L-Phe-trans-4-Hyp); (3S,6S,9aS)-3-Benzyl-6-(hydroxymethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione; L-Phenylalanyl-trans-4-hydroxy-L-proline anhydride; Diketopiperazine derivative of Phe-Hyp; c(Phe-Hyp); Phe-Hyp DKP
EINECS	Contact for details

Quality Control

Our Cyclo(L-Phenylalanyl-trans-4-Hydroxy-L-Proline) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.