Description

(Phe4)-Dermorphin (1-4) Amide CAS NO 118476-87-2 is a synthetic tetrapeptide analog of the potent opioid peptide dermorphin. This compound is of significant interest in biochemical and pharmacological research due to its high affinity and selectivity for mu-opioid receptors. It serves as a critical tool for researchers and developers in the pharmaceutical and life sciences sectors. Its defined structure makes it valuable for studying pain pathways, receptor-ligand interactions, and for the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of opioid receptor binding, signaling, and function.
• Pharmacological Development: Acts as a lead compound or molecular probe in the discovery and development of new analgesic and neuroactive drugs.
• Neuroscience Studies: Employed in experimental models to investigate pain modulation, addiction mechanisms, and central nervous system physiology.
• In Vitro Assays: Utilized in cell-based assays and high-throughput screening (HTS) platforms to evaluate biological activity and compound efficacy.
• Peptide Chemistry: Serves as a building block or intermediate in the synthesis of more complex peptide derivatives and libraries.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental scientific investigation.

Basic Information

Product Name	(Phe4)-Dermorphin (1-4) Amide
CAS No.	118476-87-2
Molecular Formula	C30H40N6O6
Molecular Weight	580.68 g/mol
Synonyms	Tyr-D-Ala-Phe-Gly-NH2; H-Tyr-D-Ala-Phe-Gly-NH2; Dermorphin (1-4) amide; [Phe4]Dermorphin(1-4)NH2; [Phe4]-Dermorphin(1-4) amide; Dermorphin tetrapeptide amide; Tyr-D-Ala-Phe-Gly amide
EINECS	Contact for details

Quality Control

Our (Phe4)-Dermorphin (1-4) Amide is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation. We provide comprehensive Certificates of Analysis (COA) detailing all specifications. Our quality management system supports compliance with relevant standards for research-grade biochemicals, ensuring reliable and reproducible results for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, DMSO, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.