Description

Glutathione Monoethyl Ester is a cell-permeable, esterified derivative of the essential antioxidant glutathione. This modification enhances its bioavailability and cellular uptake, making it a powerful agent for combating oxidative stress and supporting cellular health. It is a critical intermediate and active ingredient for manufacturers in the pharmaceutical, nutraceutical, and advanced cosmetic industries, where it is used to develop products targeting anti-aging, detoxification, and mitochondrial function.

Application

• Pharmaceutical Intermediates: Used in the synthesis of advanced therapeutics targeting liver protection, neurodegenerative diseases, and metabolic disorders.
• Nutraceutical & Dietary Supplements: A key bioactive ingredient in formulations designed for antioxidant support, immune system enhancement, and detoxification.
• Cosmeceutical & Skincare: Incorporated into high-performance serums and creams for its potent anti-aging, brightening, and protective properties against environmental damage.
• Biochemical Research: Serves as a vital tool in cell culture and molecular biology studies to modulate intracellular redox states and study oxidative stress pathways.
• Veterinary Pharmaceuticals: Used in formulations aimed at improving animal health, particularly for pets and livestock, through antioxidant support.

Basic Information

Product Name	Glutathione Monoethyl Ester
CAS No.	118421-50-4
Molecular Formula	C12H20N3O6S
Molecular Weight	334.37 g/mol
Synonyms	L-Glutathione Monoethyl Ester; γ-Glu-Cys-Gly-OEt; GSH-Monoethyl Ester; S-Glutathionyl Ethyl Ester; Reduced Glutathione Monoethyl Ester; Glutathione Ethyl Ester; (2S)-2-Amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-ethoxy-2-oxoethyl]carbamoyl}butanoic acid; NSC 335925
EINECS	Contact for details

Quality Control

Our Glutathione Monoethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical and nutraceutical applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	-15.0° to -19.0° (c=1 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.