Description

n-[2-[2-[(Dipropylamino)Methyl]-1-Piperidinyl]Ethyl]-5,6-Dihydro-6-Oxo-11H-Pyrido[2,3-B][1,4]Benzodiazepine-11-Carboxamide is a high-purity, complex heterocyclic compound designed for advanced research and pharmaceutical development. This compound is critical for its potential role as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new drug candidates, particularly in the central nervous system (CNS) and oncology fields.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel drug candidates, especially those targeting complex biological pathways.
• Research & Development: Used in academic and industrial R&D settings for pharmacological screening, structure-activity relationship (SAR) studies, and mechanism of action investigations.
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development, validation, and quality control testing in API manufacturing.
• Preclinical Studies: Employed in the early stages of drug discovery for in vitro and in vivo testing to assess efficacy, pharmacokinetics, and toxicology.
• Process Chemistry: Utilized in the development and optimization of scalable synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and pilot-scale production.

Basic Information

Product Name	n-[2-[2-[(Dipropylamino)Methyl]-1-Piperidinyl]Ethyl]-5,6-Dihydro-6-Oxo-11H-Pyrido[2,3-B][1,4]Benzodiazepine-11-Carboxamide
CAS No.	118290-26-9
Molecular Formula	C29H40N6O2
Molecular Weight	504.67 g/mol
Synonyms	11H-Pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide, N-[2-[2-[(dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-; L-689,660; L689660; L 689660; (S)-N-[2-[2-[(Dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide
EINECS	Contact for details

Quality Control

Our n-[2-[2-[(Dipropylamino)Methyl]-1-Piperidinyl]Ethyl]-5,6-Dihydro-6-Oxo-11H-Pyrido[2,3-B][1,4]Benzodiazepine-11-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.