Description

3,5-Difluoro-4-Hydroxybenzaldehyde is a versatile fluorinated aromatic aldehyde building block, distinguished by its unique substitution pattern. This compound is critical for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where the introduction of fluorine atoms enhances metabolic stability and binding affinity. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and liquid crystal industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics where fluorine substitution is advantageous.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and pesticides with improved efficacy and environmental profile.
• Liquid Crystal Materials: Used in the production of fluorinated liquid crystals for high-performance displays (LCDs) due to its ability to modify dielectric anisotropy and viscosity.
• Organic Electronic Materials: Serves as a starting material for synthesizing fluorinated organic semiconductors and charge-transport materials.
• Advanced Polymer Monomers: Incorporated into specialty polymers to impart specific properties like chemical resistance, thermal stability, or unique optical characteristics.
• Chemical Research & Development: A valuable reagent for exploring new fluorination chemistry and creating libraries of compounds for high-throughput screening.

Basic Information

Product Name	3,5-Difluoro-4-Hydroxybenzaldehyde
CAS No.	118276-06-5
Molecular Formula	C7H4F2O2
Molecular Weight	158.10 g/mol
Synonyms	4-Hydroxy-3,5-difluorobenzaldehyde; 3,5-Difluoro-4-hydroxybenzaldehyde; 3,5-Difluoro-4-formylphenol; 4-Formyl-2,6-difluorophenol; Benzaldehyde, 3,5-difluoro-4-hydroxy-; 2,6-Difluoro-4-hydroxybenzaldehyde
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-Hydroxybenzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.