Description

Somatotropin Releasing Hormone-(1-29)Nhet, 1-n-Metyr-27-Nle-28-Asn- is a synthetic peptide analog of Growth Hormone-Releasing Hormone (GHRH). This compound is of significant interest for its potent and selective stimulation of growth hormone secretion. It is primarily utilized in advanced pharmaceutical research and development, particularly in endocrinology and metabolic studies. The peptide offers a valuable tool for investigating growth hormone pathways and developing novel therapeutic agents.

Application

• Pharmaceutical Research & Development: A key reference standard and active ingredient in preclinical studies targeting growth hormone deficiencies and related metabolic disorders.
• Endocrinology Studies: Used in laboratory research to elucidate the mechanisms of growth hormone release and pituitary function.
• Biochemical Assay Development: Serves as a critical component in the development and validation of bioassays and immunoassays for GHRH activity.
• Peptide Chemistry & Analog Synthesis: Acts as a lead compound or intermediate for the synthesis of novel GHRH analogs with improved stability or efficacy profiles.
• Metabolic Disorder Research: Investigated for potential applications in conditions like muscle-wasting diseases, aging research, and obesity studies.

Basic Information

Product Name	Somatotropin Releasing Hormone-(1-29)Nhet, 1-n-Metyr-27-Nle-28-Asn-
CAS No.	118202-57-6
Molecular Formula	C149H246N44O42
Molecular Weight	3359.8 g/mol (theoretical)
Synonyms	GHRH (1-29) amide, human; Somatoliberin (1-29) amide, human; Growth Hormone-Releasing Factor (1-29) amide; hGRF(1-29)NH2; [Nle27]hGRF(1-29)-NH2; Sermorelin Acetate (related analog); GRF (1-29); Growth Hormone Releasing Peptide-29
EINECS	Contact for details

Quality Control

Our peptide products are manufactured and controlled under a strict quality management system. Each batch of Somatotropin Releasing Hormone-(1-29)Nhet, 1-n-Metyr-27-Nle-28-Asn- undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular ion peak consistent with theoretical mass
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.