Description

Bovine Parathyroid Hormone-(7-34) Amide,12-Trp,34-Tyr- CAS NO 118102-97-9 is a synthetic peptide fragment derived from bovine parathyroid hormone, specifically the biologically active region. This compound is a critical research tool for studying calcium and phosphate metabolism, bone physiology, and the mechanisms of parathyroid hormone action. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in metabolic and endocrine disorder research, as well as in the development of novel therapeutic agents.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of parathyroid hormone (PTH) receptor binding, signal transduction, and biological activity.
• Drug Discovery & Development: Serves as a key intermediate or pharmacological tool in screening assays and the development of PTH-related therapeutics for osteoporosis and other bone diseases.
• Endocrinology Studies: Essential for investigating the role of PTH in calcium homeostasis, renal function, and bone remodeling in experimental models.
• Biochemical Assay Development: Employed in the calibration and validation of immunoassays (e.g., ELISA, RIA) and other analytical methods designed to detect PTH or its fragments.
• Academic & Clinical Research: Supports fundamental research into metabolic bone diseases, hyperparathyroidism, and hypoparathyroidism.

Basic Information

Product Name	Bovine Parathyroid Hormone-(7-34) Amide,12-Trp,34-Tyr-
CAS No.	118102-97-9
Molecular Formula	C₁₄₈H₂₃₈N₄₈O₄₀S₂
Molecular Weight	~3350.8 g/mol
Synonyms	PTH (7-34) amide, bovine; [Trp12, Tyr34]-bPTH-(7-34)-NH₂; Bovine Parathyroid Hormone Fragment 7-34 amide; Parathyroid Hormone (7-34), bovine, amide; bPTH-(7-34)-NH₂ (12-Trp,34-Tyr); PTH-related peptide fragment; [Trp12,Tyr34]bPTH(7-34)amide
EINECS	Contact for details

Quality Control

Our Bovine Parathyroid Hormone-(7-34) Amide,12-Trp,34-Tyr- is produced under stringent conditions to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and analytical results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider desiccant.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.