Description

H-Glu(Ochex)-OH is a protected glutamic acid derivative where the γ-carboxylic acid group is esterified with cyclohexanol. This compound is a crucial building block in peptide synthesis and medicinal chemistry, offering a strategic handle for selective deprotection and further functionalization. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic peptides and chemical probes.

Application

• Peptide Synthesis: Serves as a key protected amino acid intermediate in solid-phase and solution-phase peptide synthesis (SPPS).
• Medicinal Chemistry: Used in the research and development of peptide-based drugs and bioactive compounds targeting various diseases.
• Bioconjugation: Acts as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or reporter groups.
• Chemical Biology: Employed in the synthesis of chemical tools and probes for studying enzyme function and protein-protein interactions.
• API Intermediate: Functions as a critical intermediate in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Material Science: Potential use in the development of specialized polymers and biomaterials with tailored properties.

Basic Information

Product Name	H-Glu(Ochex)-OH
CAS No.	117969-50-3
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	Fmoc-Glu(OcHex)-OH; N-α-Fmoc-L-glutamic acid γ-cyclohexyl ester; L-Glutamic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 5-cyclohexyl ester; γ-Cyclohexyl L-glutamate, N-Fmoc-protected; Fmoc-Glu(OcHex)-OH; Fmoc-L-glutamic acid 5-cyclohexyl ester; Boc-Glu(OcHex)-OH (for Boc-protected variant); Protected glutamic acid cyclohexyl ester
EINECS	Contact for details

Quality Control

Our H-Glu(Ochex)-OH is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via NMR and mass spectrometry. We provide Certificates of Analysis (COA) with every shipment, detailing all specifications and test results to ensure compliance with your research and cGMP-grade manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.