Description

H-Tyr-Tyr-Leu-Oh CAS NO 117961-24-7 is a synthetic tripeptide composed of two tyrosine residues and one leucine residue, featuring a free C-terminal carboxylic acid. This compound is of significant interest in biochemical research and pharmaceutical development due to its structural role as a model for tyrosine-rich peptide sequences. It serves as a critical intermediate or reference standard for researchers and manufacturers in the life sciences sector. Target users include peptide synthesis companies, academic research institutions, and pharmaceutical R&D departments focusing on neuropeptides, enzyme substrates, or novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Used in the research and development of novel peptide-based therapeutics and drug candidates.
• Biochemical Research: Serves as a model substrate or standard in enzymatic studies, particularly those involving tyrosine kinases or phosphatases.
• Peptide Synthesis: Acts as a key building block for the solid-phase or solution-phase synthesis of longer, more complex peptide chains.
• Reference Standard: Employed in analytical laboratories for method development, validation, and quality control of peptide products via HPLC or MS.
• Neuroscience Studies: Investigated for potential bioactivity related to tyrosine-containing neuropeptide analogs.
• Cosmeceutical R&D: Explored as a potential active ingredient in premium skincare formulations targeting specific biological pathways.

Basic Information

Item	Details
Product Name	H-Tyr-Tyr-Leu-Oh
CAS No.	117961-24-7
Molecular Formula	C27H37N3O7
Molecular Weight	515.60 g/mol
Synonyms	H-Tyr-Tyr-Leu-OH; L-Leucine, L-tyrosyl-L-tyrosyl-; Tyr-Tyr-Leu; TYL; YYL; L-Tyrosyl-L-tyrosyl-L-leucine; (2S)-2-[[(2S)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoic acid; H-Y-Y-L-OH
EINECS	Contact for details

Quality Control

Our H-Tyr-Tyr-Leu-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral purity analysis to ensure the highest standards. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP guidelines for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (Titration)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.