Description

2-(Benzyloxy)-5-(Trifluoromethyl)Aniline is a high-purity, specialized aromatic amine derivative featuring a benzyl-protected phenolic ether and a trifluoromethyl substituent. This compound is a crucial advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis, valued for its unique electronic properties imparted by the fluorine atoms. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for the development of specialty chemicals used in electronic displays and organic light-emitting diodes (OLEDs).
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of specialized dyes and pigments with tailored color and fastness properties.
• Polymer Chemistry: Employed as a monomer or cross-linking agent in the synthesis of high-performance polymers with specific thermal or chemical resistance.
• Chemical Research & Development: A valuable reagent for academic and industrial research in medicinal chemistry and material science for structure-activity relationship (SAR) studies.

Basic Information

Item	Detail
Product Name	2-(Benzyloxy)-5-(Trifluoromethyl)Aniline
CAS No.	117901-14-1
Molecular Formula	C14H12F3NO
Molecular Weight	267.25 g/mol
Synonyms	5-(Trifluoromethyl)-2-(benzyloxy)aniline; 2-(Benzyloxy)-5-(trifluoromethyl)benzenamine; 2-Benzyloxy-5-trifluoromethylaniline; 2-Amino-4-(benzyloxy)benzotrifluoride; 4-(Benzyloxy)-2-(trifluoromethyl)aniline; Benzenamine, 2-(phenylmethoxy)-5-(trifluoromethyl)-; [2-(Benzyloxy)-5-(trifluoromethyl)phenyl]amine
EINECS	Contact for details

Quality Control

Our production of 2-(Benzyloxy)-5-(Trifluoromethyl)Aniline adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality system is designed to support cGMP compliance for pharmaceutical applications, ensuring traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.