Description

Neurotoxin I, Stichodactyla Helianthus is a potent peptide neurotoxin isolated from the Caribbean sea anemone *Stichodactyla helianthus*. This compound is of significant value for its high specificity and affinity in blocking voltage-gated potassium channels (Kv channels). It is an essential research-grade biochemical for neuroscientists, pharmacologists, and toxicologists engaged in ion channel studies, neurological disorder research, and the development of novel therapeutic agents.

Application

• Neuroscience Research: A critical tool for studying the structure, function, and pharmacology of voltage-gated potassium (Kv) channels, particularly Kv1.1, Kv1.2, and Kv1.6 subtypes.
• Drug Discovery & Development: Used in high-throughput screening (HTS) assays to identify and characterize new modulators of potassium channels for potential treatments in autoimmune diseases, neurological disorders, and cardiac conditions.
• Toxicology Studies: Serves as a reference standard in marine toxin research and for understanding the mechanism of action of cnidarian venoms.
• Biochemical Reagent: Employed in the development of sensitive detection methods and biosensors for toxin analysis.
• Academic & Pharmaceutical R&D: Fundamental reagent for basic research in cellular electrophysiology, signal transduction pathways, and synaptic transmission.

Basic Information

Product Name	Neurotoxin I, Stichodactyla Helianthus
CAS No.	117860-13-6
Molecular Formula	C198H310N60O59S6
Molecular Weight	~4550 g/mol
Synonyms	ShK Toxin; Sea Anemone Neurotoxin ShK; Stichodactyla toxin; Potassium channel toxin ShK; ShK peptide; Neurotoxin ShK-I; ShK-F6CA; UNII-6V3X1B52VW
EINECS	Contact for details

Quality Control

Our Neurotoxin I, Stichodactyla Helianthus is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical characterization, including mass spectrometry (MS) for molecular weight confirmation and HPLC for purity assessment. Certificates of Analysis (COA) detailing purity, potency, and analytical data are provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Potency (Biological Assay)	Contact for details
Water Content (KF)	≤ 5.0%
Endotoxin Level (LAL)	< 1.0 EU/µg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.