Description

(2S,1'S,2'S)-2-(Carboxycyclopropyl)Glycine is a high-purity, non-proteinogenic amino acid derivative featuring a unique cyclopropane ring structure. This compound is a potent and selective agonist for group II metabotropic glutamate receptors (mGluR2/3), making it a critical research tool in neuroscience and pharmacology. It is primarily utilized by pharmaceutical researchers, academic institutions, and R&D laboratories focused on neurological disorders, receptor characterization, and drug discovery programs.

Application

• Neuroscience Research: As a selective mGluR2/3 agonist for studying synaptic transmission, neural plasticity, and the pathophysiology of neurological conditions.
• Pharmacological Studies: Used in in vitro and in vivo assays to investigate receptor function and screen for potential therapeutic compounds targeting glutamate pathways.
• Biochemical Standard: Serves as a reference standard for analytical method development, validation, and quality control in pharmaceutical analysis.
• Drug Discovery & Development: A key intermediate or pharmacophore in the design and synthesis of novel central nervous system (CNS) active agents.
• Academic Research: Employed in university and institutional labs for fundamental research on excitatory amino acids and their role in the brain.

Basic Information

Product Name	(2S,1'S,2'S)-2-(Carboxycyclopropyl)Glycine
CAS No.	117857-93-9
Molecular Formula	C7H9NO4
Molecular Weight	171.15 g/mol
Synonyms	L-CCG-I; (1S,2S,3S)-2-(Carboxycyclopropyl)glycine; (S)-2-(1'-Carboxy-2',3'-methanocyclopropyl)glycine; CCG; (2S)-2-[(1S,2S)-1-Carboxy-2,3-methanocyclopropyl]glycine; L-2-(Carboxycyclopropyl)glycine; Group II mGluR Agonist
EINECS	Contact for details

Quality Control

Our (2S,1'S,2'S)-2-(Carboxycyclopropyl)Glycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (NMR, IR, MS). A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.