Description

8-Azatryptophan is a high-purity, non-proteinogenic amino acid analog of tryptophan, where a nitrogen atom replaces a carbon in the indole ring. This structural modification makes it a valuable biochemical tool and a key synthetic intermediate in advanced research and pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, proteomics, and the synthesis of novel bioactive compounds. The product is supplied under stringent quality control to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly protease inhibitors and enzyme modulators.
• Biochemical Research: Used as a probe in enzyme kinetics studies and protein structure-function analysis to understand tryptophan metabolism pathways.
• Peptide Synthesis: Incorporation into custom peptides to study fluorescence quenching, protein folding, and receptor-ligand interactions.
• Metabolic Pathway Studies: Serves as a tracer or inhibitor in research focused on the kynurenine and serotonin biosynthesis pathways.
• Reference Standard: Used as an analytical standard in HPLC and LC-MS methods for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	8-Azatryptophan
CAS No.	117782-75-9
Molecular Formula	C11H11N3O2
Molecular Weight	217.23 g/mol
Synonyms	8-Aza-DL-tryptophan; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, α-amino-; 2-Amino-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)propanoic acid; DL-8-Azatryptophan; 8-Azatryptophan, DL-; Tryptazan (related analog); Azaindolealanine
EINECS	Contact for details

Quality Control

Our 8-Azatryptophan is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets the high standards required for research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can support development projects with custom purity grades and analytical data packages upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.